Introduction: The glandular odontogenic cyst (GOC) is a rare, locally aggressive and potentially recurrent cyst of jaws which lead in diagnostic and therapeutic challenges. Since 1992, 111 cases of GOC have been reported, with 0.2% incidence among odontogenic cysts.Case Presentation: The patient was a 33-year-old woman who came to the department of oral medicine with a complaint of facial swelling. After taking her history, and conducting clinical, radiological, and histopathologic examinations, the diagnosis of GOC was made.Conclusions: Glandular odontogenic cyst is an uncommon and relatively aggressive cyst with a high recurrence rate. Clinical and radiological evaluations are needed together with careful histopathologic evaluations for diagnosis. Oral medicine specialists should be aware of its characteristic features and make an accurate diagnosis so appropriate management can follow.